Tomato (Lycopersicon esculentum Mill.) juice restored the number of Leydig cells, and the diameter of the seminiferous tubules of mice (Mus musculus) exposed to lead acetate

Lead is a harmful pollutant from engine exhaust that causes free radicals and has detrimental effects on the testicular tissue. This study aimed to determine of tomato juice number Leydig cells diameter seminiferous tubules mice exposed lead acetate. Twenty-five male were divided into five groups. Mice in control (C-) group given placebos. Meanwhile, C+, T1, T2, T3 groups acetate at dose 100 mg/kg BW/day for 14 days respectively 0, 0.16, 0.32, 0.64 mL/day day 8 35. On 36, all sacrificed, testes collected histological preparation. The result showed exposure C+ decreased (p <0.05) compared C-. Administration increased tubule C- However, administration T2 group. In conclusion, an effective 0.32 restored cell